S.E.M.I.: Side Effects May Include... – Release Date, Platforms, Trailer & Gameplay

S.E.M.I.: Side Effects May Include...
Release dateReleased on Nov 20, 2025
StatusReleased
Best forHack and slash/Beat 'em up players exploring games on PC (Microsoft Windows)
RatingNo rating yet
Review coverageReview data unclear
Player signalSignal still forming

What to Know About S.E.M.I.: Side Effects May Include...

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

About S.E.M.I.: Side Effects May Include...

S.E.M.I.: Side Effects May Include... was released on Nov 20, 2025. It is available on PC (Microsoft Windows). This game falls under the Hack and slash/Beat 'em up, Indie, Arcade genres.

On this page, you can view the latest information about S.E.M.I.: Side Effects May Include..., including its release date, platforms, trailer, screenshots, and similar games to help you decide if it is worth playing.

Screenshots

Game screenshot
Game screenshotGame screenshotGame screenshotGame screenshot

Games Like S.E.M.I.: Side Effects May Include... – Similar Games to Try

Similar Hack and slash/Beat 'em up Games – Best Hack and slash/Beat 'em up Games to Play

View all Hack and slash/Beat 'em up games and top picks →

More Hack and slash/Beat 'em up Games Like S.E.M.I.: Side Effects May Include... on PC (Microsoft Windows) – Similar Games to Try

View all PC (Microsoft Windows) games and top picks →

Discover More Games – Browse by Platform, Genre, and Release